Product: PFI-3 (hydrochloride)
Integrin alpha L/CD11a Antibody (HI111) Summary
| Immunogen |
The immunogen for this antibody was CD11a.
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| Isotype |
IgG1 Kappa
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| Clonality |
Monoclonal
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| Host |
Mouse
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| Gene |
ITGAL
|
| Purity |
Protein A or G purified
|
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Applications/Dilutions
| Dilutions |
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| Application Notes |
The HI111 antibody has been tested by flow cytometric analysis of human peripheral blood leukocytes. This can be used at less than or equal to 1 ug per test. Cell number should be determined empirically but can range from 10^5to 10^8cells/test.
|
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
Aqueous, may contain carrier protein/stabilizer.
|
| Preservative |
0.09% Sodium Azide
|
| Concentration |
0.5 mg/ml
|
| Purity |
Protein A or G purified
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Alternate Names for Integrin alpha L/CD11a Antibody (HI111)
- CD11 antigen-like family member A
- CD11a antigen
- CD11a
- CD11Aantigen CD11A (p180), lymphocyte function-associated antigen 1, alphapolypeptide
- Integrin alpha L
- integrin alpha-L
- integrin gene promoter
- integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen1; alpha polypeptide)
- ITGAL
- Leukocyte adhesion glycoprotein LFA-1 alpha chain
- Leukocyte function-associated molecule 1 alpha chain
- LFA-1 alpha
- LFA-1
- LFA1A
- LFA-1A
- Ly-15
- Ly-21
- lymphocyte function-associated antigen 1
Background
The HI111 monoclonal antibody reacts with human CD11a, the 180 kDa integrin alphaL, also known as the lymphocyte function associated antigen-1 (LFA-1) alpha chain. LFA-1, formed by non-covalent association of CD11a with CD18 (integrin beta2), serves as an important adhesion molecule involved in lymphocyte and granulocyte function. CD54 (ICAM-1), CD102 (ICAM-2), and CD50 (ICAM-3) are ligands for LFA-1. CD11a is expressed by all leukocytes.