TLR11 Antibody Summary
| Immunogen |
Antibody was raised against a peptide corresponding to 16 amino acids between the middle and carboxy terminus of mouse TLR11. The immunogen is located within the last 50 amino acids of TLR11.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
TLR11
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| Purity |
Ion exchange chromatography
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Applications/Dilutions
| Dilutions |
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| Application Notes |
TLR11 antibody polyclonal antibody can be used for detection of TLR11 by Western blot at 0.5 to 2 mg/ml.
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| Control Peptide |
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Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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| Buffer |
PBS
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| Preservative |
0.02% Sodium Azide
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| Concentration |
1 mg/ml
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| Purity |
Ion exchange chromatography
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Alternate Names for TLR11 Antibody
- Gm287
- hgnc31753
- TLR11
- Toll like receptor 11
Background
Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system.