Product: Dodecanoic acid ingenol ester
RPAIN Antibody Summary
| Immunogen |
Antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human RPA IP. The immunogen is located within the last 50 amino acids of RPA Interacting Protein.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
RPAIN
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
This antibody is useful in ELISA, Western Blot, Immunohistochemistry-Paraffin. RPA Interacting Protein antibody can be used for detection of RPA Interacting Protein by Western blot at 0.5 – 1 mg/ml.
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| Control Peptide |
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Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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| Buffer |
PBS
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| Preservative |
0.02% Sodium Azide
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| Concentration |
1 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for RPAIN Antibody
- FLJ25625
- FLJ30490
- FLJ42429
- hRIP
- MGC4189
- nuclear transporter
- RAP interaction protein
- RIPHRIP
- RPA interacting protein
- RPA-interacting protein
Background
Replication protein A (RPA) is a single-stranded-DNA binding protein involved in numerous eukaryotic DNA processes including replication, repair and recombination. RPA interacting protein (RPA IP) has been identified as an adapter protein that is involved in RPA nuclear import instead of the prototypical importin proteins that normally mediate nuclear import. Multiple isoforms of RPA IP are known to exist, with the longest isoform localized to the cytoplasm. Isoform 2 is sumoylated and is located in the PML nuclear body within the nucleus. It has been suggested that this isoform mediates the localization of the RPA complex into the PML nuclear body, thereby participating in RPA function in DNA metabolism.