Mycobacterium Tuberculosis ESAT6 Antibody (RSB14) Summary
| Immunogen |
ESAT antigen.
|
| Isotype |
IgG1
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Purity |
Protein G purified
|
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|
Applications/Dilutions
| Dilutions |
|
Reactivity Notes
Chemical
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
0.09% Sodium Azide
|
| Purity |
Protein G purified
|
Alternate Names for Mycobacterium Tuberculosis ESAT6 Antibody (RSB14)
- 6 kDa early secretory antigenic target ESXA
- 6 kDa early secretory antigenic target
- ESAT 6
- esaT6
- ESXA
Background
The ESAT6 antigen from Mycobacterium tuberculosis is a dominant target for cell mediated immunity in the early phase of tuberculosis (TB) in TB patients as well as in various animal models. ESAT6 is not found in M. bovis BCG. Its function is not known but it elicits high level of IFN-gamma from memory effector cells during the first phase of a protective immune response.