Integrin alpha 4/CD49d Antibody (9C10 (MFR.4.B)) [Alexa Fluor® 647] Summary
| Immunogen |
Mouse LyD9 haematopoietic progenitor cells
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| Localization |
Type I membrane protein
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| Specificity |
NB100-64905 recognizes murine alpha 4 integrin (CD49d), a 150kD glycoprotein that can associate with either beta 1 integrin (CD29) or beta 7 integrin to form heterodimers CD49d/CD29 (VLA-4) and alpha4/beta7 (LPAM-1) respectively. CD49d is expressed on most lymphocytes, granulocytes, monocytes and thymocytes. The primary ligands for CD49d are CD106 (VCAM-1), fibronectin and MAdCAM-1. Clone 9C10 (MFR4.B) is reported to significantly inhibit binding of CD49d to CD106 but only when used in combination with clone R1-2 (1) Removal of sodium azide is recommended prior to use in functional assays.
|
| Isotype |
IgG2a
|
| Clonality |
Monoclonal
|
| Host |
Rat
|
| Gene |
ITGA4
|
| Purity |
Protein G purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Optimal dilution of this antibody should be experimentally determined.
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Packaging, Storage & Formulations
| Storage |
Store at 4C in the dark.
|
| Buffer |
50mM Sodium Borate
|
| Preservative |
0.05% Sodium Azide
|
| Purity |
Protein G purified
|
Notes
This product is provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or [email protected].
Alternate Names for Integrin alpha 4/CD49d Antibody (9C10 (MFR.4.B)) [Alexa Fluor® 647]
- 269C wild type
- CD49 antigen-like family member D
- CD49d antigen
- CD49d
- CD49Dantigen CD49D, alpha-4 subunit of VLA-4 receptor
- IA4
- Integrin alpha 4
- integrin alpha-4 subunit
- integrin alpha-4
- Integrin alpha-IV
- integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
- ITGA4
- MGC90518
- very late activation protein 4 receptor, alpha 4 subunit
- VLA-4 subunit alpha
- VLA-4