CNOT7 Antibody Summary
| Immunogen |
This CAF-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-61 amino acids from the N-terminal region of human CAF-1.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
CNOT7
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| Purity |
Protein A purified
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Applications/Dilutions
| Dilutions |
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Reactivity Notes
Reacts with Human. Predicted to react with Bovine, Chicken, Mouse, Xenopus and Zebrafish.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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| Buffer |
PBS
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| Preservative |
0.09% Sodium Azide
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| Purity |
Protein A purified
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Alternate Names for CNOT7 Antibody
- BTG1 binding factor 1
- BTG1-binding factor 1
- CAF-1
- CAF1carbon catabolite repressor protein (CCR4)-associative factor 1
- CCR4-associated factor 1
- CCR4-NOT transcription complex subunit 7
- CCR4-NOT transcription complex, subunit 7
- hCAF-1
Background
The protein encoded by this gene binds to ananti-proliferative protein, B-cell translocation protein 1, whichnegatively regulates cell proliferation. Binding of the twoproteins, which is driven by phosphorylation of theanti-proliferative protein, causes signaling events in celldivision that lead to changes in cell proliferation associated withcell-cell contact. The protein has both mouse and yeast orthologs.Alternate splicing of this gene results in two transcript variantsencoding different isoforms.