ZRSR2 Antibody

Product: ARV-826

ZRSR2 Antibody Summary

Immunogen
Synthetic peptides corresponding to ZRSR2 (zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2) The peptide sequence was selected from the C terminal of ZRSR2. Peptide sequence HHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSHKRT
Specificity
This product is specific to Subunit or Isofrom: -related protein 2.
Clonality
Polyclonal
Host
Rabbit
Gene
ZRSR2
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Application Notes
This is a rabbit polyclonal antibody against ZRSR2 and was validated on Western Blot and immunohistochemistry-p

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS and 2% Sucrose
Preservative
0.09% Sodium Azide
Purity
Protein A purified

Notes

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Alternate Names for ZRSR2 Antibody

  • CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2
  • Renal carcinoma antigen NY-REN-20
  • U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-relatedprotein 2
  • U2 small nuclear ribonucleoprotein auxiliary factor, small subunit 2
  • U2(RNU2) small nuclear RNA auxiliary factor 1-like 2MGC142014
  • U2AF1L2
  • U2AF1RS2MGC142040
  • U2AF1-RS2U2AF35-related protein
  • URPU2 small nuclear RNA auxiliary factor 1-like 2
  • zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2

Background

ZRSR2 is an essential splicing factor. The protein associates with the U2 auxiliary factor heterodimer, which is required for the recognition of a functional 3 splice site in pre-mRNA splicing, and may play a role in network interactions during spliceosome assembly.This gene encodes U2AF small subunit related protein 2 which is an essential splicing factor. This protein is associated with the U2AF heterodimer composed of a large and a small subunit. It specifically interacts with the large subunit through an U2AF small subunit homologous region, and with SR proteins through its RS domain. This protein and U2AF small subunit are not functionally redundant.

PMID: 25062042