VE-Cadherin Antibody (MM0012-8A03) Summary
| Immunogen |
This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse immunized with human ICAM1 N-terminal recombinant protein.
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| Marker |
Endothelial Cell Marker
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| Specificity |
VE Cadherin (MM0012-8A03)
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| Isotype |
IgG1
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| Clonality |
Monoclonal
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| Host |
Mouse
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| Gene |
CDH5
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| Purity |
Protein G purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
In western blots this antibody shown no cross-reactivity with E-Cadherin, and P-Cadherin.
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
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| Buffer |
A 0.2 um filtered solution in PBS
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| Preservative |
No Preservative
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| Concentration |
LYOPH
|
| Purity |
Protein G purified
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| Reconstitution Instructions |
Reconstitute with 0.5 ml sterilized PBS to a final concentration of 0.2 mg/ml.
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Alternate Names for VE-Cadherin Antibody (MM0012-8A03)
- 7B4 antigen
- 7B4
- cadherin 5, type 2 (vascular endothelium)
- cadherin 5, type 2, VE-cadherin (vascular epithelium)
- Cadherin-5
- CD144 antigen
- CD144
- CDH5
- endothelial-specific cadherin
- FLJ17376
- Vascular endothelial cadherin
- VECadherin
- VE-Cadherin
Background
Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha catenin forming a link to the cytoskeleton.