IKB zeta Antibody (1E8) Summary
| Immunogen |
Full length human recombinant protein of human NFKBIZ (NP_113607) produced in E.coli.
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| Isotype |
IgG1
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| Clonality |
Monoclonal
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| Host |
Mouse
|
| Gene |
NFKBIZ
|
| Purity |
Immunogen affinity purified
|
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Applications/Dilutions
| Dilutions |
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Reactivity Notes
Human
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
|
| Preservative |
0.02% Sodium Azide
|
| Purity |
Immunogen affinity purified
|
Alternate Names for IKB zeta Antibody (1E8)
- FLJ30225
- FLJ34463
- ikappaBzeta
- I-kappa-B-zeta
- IkappaB-zeta
- ikbzeta
- IkB-zeta
- IL-1 inducible nuclear ankyrin-repeat protein
- INAPIkappa B-zeta variant 3
- MAILIKBZikB-zeta
- Molecule possessing ankyrin repeats induced by lipopolysaccharide
- NF-kappa-B inhibitor zeta
- nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor
Background
This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].