FKBP52/FKBP4 Antibody (4D3) Summary
| Immunogen |
Recombinant human FKBP4 (1-459aa) purified from E. coli (NP_002005).
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| Specificity |
This antibody is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human FKBP4 protein.
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| Isotype |
IgG2b Kappa
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| Clonality |
Monoclonal
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| Host |
Mouse
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| Gene |
FKBP4
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| Purity |
Protein G purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
For IHC: Antigen retrieval in 0.1M sodium citrate buffer and detection using Diaminobenzidine (DAB) is recommended.
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
|
| Theoretical MW |
52 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
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| Publications |
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Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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| Buffer |
PBS (pH 7.4) and 10% Glycerol
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| Preservative |
0.02% Sodium Azide
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| Concentration |
1.0 mg/ml
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| Purity |
Protein G purified
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Alternate Names for FKBP52/FKBP4 Antibody (4D3)
- 51 kDa FK506-binding protein
- 52 kDa FKBP
- 59 kDa immunophilin
- EC 5.2.1.8
- FK506 binding protein 4, 59kDa
- FK506-binding protein 4 (59kD)
- FK506-binding protein 4
- FKBP4
- FKBP-4
- FKBP51
- FKBP52
- FKBP-52
- FKBP52T-cell FK506-binding protein, 59kD
- FKBP59
- FKBP5952 kDa FK506-binding protein
- HBI
- HSP binding immunophilin
- Hsp56
- HSP-binding immunophilin
- Immunophilin FKBP52
- p52
- p59
- peptidyl-prolyl cis-trans isomerase FKBP4
- peptidylprolyl cis-trans isomerase
- PPIase FKBP4
- PPIase
- rotamase
Background
FKBP4, also known as FKBP52, is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. It is a component of unactivated mammalian steroid receptor complexes and may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors. It interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes. Recombinant human FKBP4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.