PP2C gamma/PPM1G Antibody (k1G6) Summary
| Immunogen |
Recombinant human PPM1G (317-546aa) purified from E. coli
|
| Specificity |
Anti-human PPM1G mAb, clone k1G6, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PPM1G protein.
|
| Isotype |
IgG1
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| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
PPM1G
|
| Purity |
Protein G purified
|
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Applications/Dilutions
| Dilutions |
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Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4) and 10% Glycerol
|
| Preservative |
0.02% Sodium Azide
|
| Concentration |
1.0 mg/ml
|
| Purity |
Protein G purified
|
Alternate Names for PP2C gamma/PPM1G Antibody (k1G6)
- EC 3.1.3.16
- MGC1675
- MGC2870
- PP2C gamma
- PP2C, gamma
- PP2CG
- PP2CGAMMA
- PP2C-gamma
- PPM1C
- PPM1G
- PPP2CG
- Protein phosphatase 1C
- protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
- protein phosphatase 1G
- protein phosphatase 2, catalytic subunit, gamma isoform
- protein phosphatase 2C gamma isoform
- Protein phosphatase 2C isoform gamma
- Protein phosphatase magnesium-dependent 1 gamma
- protein phosphatase, Mg2+/Mn2+ dependent, 1G
Background
PPM1G (Protein phosphatase 1G) is a member of the PP2C family of Serine/threonine protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. The human Ser/Thr phosphatase PPM1G promotes spliceosome assembly. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome.