IL-1 beta/IL-1F2 Antibody (11E5) Summary
| Immunogen |
recombinant human IL-1, beta.
|
| Specificity |
This binds to the IL-1, beta molecule. It does not inhibit the biological activity of IL-1.
|
| Isotype |
IgG2b
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
IL1B
|
| Purity |
Protein A purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Detection of IL-1, beta in two-site immunoassay. We recommend using mixture of NB120-8319 and NB100-73053 for coating and NB100-73054 for labeling.
|
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
0.09% Sodium Azide
|
| Purity |
Protein A purified
|
Alternate Names for IL-1 beta/IL-1F2 Antibody (11E5)
- catabolin
- IL1 beta
- IL-1 beta
- IL-1
- IL1B
- IL-1b
- IL1-BETA
- IL-1F2
- IL1F2IL-1 beta
- interleukin 1, beta
- interleukin-1 beta
- preinterleukin 1 beta
- pro-interleukin-1-beta
Background
Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also is released from several other cell types, and is thought to play a key role in inflammatory and immune responses. The two closely related agents, interleukin1 alpha (IL1 alpha) and interleukin1 beta (IL1 beta) bind to the same cell surface receptor, elicit nearly identical biological responses and share 25% homology in their amino acid sequence.