Mouse anti-Human IgG Fc fragment Secondary Antibody (2A11) Summary
| Immunogen |
This clone has been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunised with IgG from human serum.
|
| Specificity |
Class-specific for human IgG (Fab-region specific). No cross-reactivity with human IgA, IgM, IgE.
|
| Isotype |
IgG2b
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Purity |
Protein G purified
|
Applications/Dilutions
| Reviewed Applications |
|
Reactivity Notes
Cross-reacts with Human.
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
PBS, pH 7.4
|
| Preservative |
0.09% Sodium Azide
|
| Purity |
Protein G purified
|
Background
Immunoglobulin G (IgG), is one of the most abundant proteins in human serum with normal levels between 8-17 mg/ml in adult blood. IgG is important for our defence against microorganisms and the molecules are produced by B lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants.