Lysyl tRNA synthetase Antibody (8G12C1) Summary
| Immunogen |
Purified recombinant fragment of KARS(aa90-174) expressed in E. Coli.
|
| Isotype |
IgG1
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
KARS
|
| Purity |
Unpurified
|
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|
Applications/Dilutions
| Dilutions |
|
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
Ascites
|
| Preservative |
0.03% Sodium Azide
|
| Purity |
Unpurified
|
Alternate Names for Lysyl tRNA synthetase Antibody (8G12C1)
- CMTRIB
- EC 6.1.1
- EC 6.1.1.6
- KARS2
- KIAA0070
- KRS
- lysine tRNA ligase
- Lysine–tRNA ligase
- lysRS
- lysyl-tRNA synthetase
Background
lysyl-tRNA synthetase. Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.