FGF basic/FGF2 Antibody (2H5G2C11) Summary
| Immunogen |
Purified recombinant fragment of FGF2 expressed in E. Coli.
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| Clonality |
Monoclonal
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| Host |
Mouse
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| Gene |
FGF2
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| Purity |
Unpurified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
This antibody is useful in Western Blot, Immunohistochemistry-Paraffin, ELISA. May be useful in Immunohistochemistry-Frozen.
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| Publications |
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Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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| Buffer |
Ascites
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| Preservative |
0.03% Sodium Azide
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| Purity |
Unpurified
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Alternate Names for FGF basic/FGF2 Antibody (2H5G2C11)
- basic fibroblast growth factor bFGF
- Basic fibroblast growth factor
- bFGF
- FGF basic
- FGF2
- FGF-2
- FGF2AS
- FGFBprostatropin
- fibroblast growth factor 2 (basic)
- GFG1
- HBGF-2
- HBGH-2
- heparin-binding growth factor 2
- NUDT6
- Prostatropin
Background
FGF basic (FGF2) is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. FGF2 is involved in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. FGF2 mRNA contains multiple polyadenylation sites, and is alternatively translated from AUG and non-AUG (CUG) initiation codons resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.