CD19 Antibody (2E2B6B10) Summary
| Immunogen |
Purified recombinant fragment of human CD19 expressed in E. Coli.
|
| Isotype |
IgG2b
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
CD19
|
| Purity |
Protein A or G purified
|
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Applications/Dilutions
| Dilutions |
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Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS
|
| Preservative |
0.03% Sodium Azide
|
| Purity |
Protein A or G purified
|
Alternate Names for CD19 Antibody (2E2B6B10)
- B4
- B-lymphocyte antigen CD19
- B-lymphocyte surface antigen B4
- CD19 antigen
- CD19 molecule
- CD19
- CVID3
- Differentiation antigen CD19
- Leu-12
- MGC12802
- T-cell surface antigen Leu-12
Background
This antibody reacts with mouse CD19, a 95 kDa transmembrane glycoprotein. CD19 is expressed by B cells during all stages of development excluding the terminally differentiated plasma cells. Follicular dendritic cells also express CD19. Together CD21, CD81, MHC class II, and CD19 form a multimolecular complex that associates with the BCR. Signaling through CD19 induces tyrosine phosphorylation, calcium flux and proliferation of B cells.