FLJ10808 Antibody

Product: Tivozanib

FLJ10808 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human FLJ10808. The exact sequence is proprietary.
Predicted Species
Bovine (91%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
UBA6
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
Application Notes
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
118 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Expected cross reactivity based on sequence homology: Mouse (88%), Rat (89%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 20% Glycerol
Preservative
0.01% Thimerosal
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for FLJ10808 Antibody

  • E1-L2
  • FLJ10808
  • FLJ23367
  • Monocyte protein 4
  • MOP4
  • MOP-4
  • UBA6, ubiquitin-activating enzyme E1
  • UBE1L2
  • Ubiquitin-activating enzyme 6
  • ubiquitin-activating enzyme E1-like 2
  • Ubiquitin-activating enzyme E1-like protein 2
  • ubiquitin-like modifier activating enzyme 6
  • ubiquitin-like modifier-activating enzyme 6

Background

Modification of proteins with ubiquitin (UBB; MIM 191339) or ubiquitin-like proteins controls many signaling networks and requires a ubiquitin-activating enzyme (E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin protein ligase (E3). UBE1L2 is an E1 enzyme that initiates the activation and conjugation of ubiquitin-like proteins (Jin et al., 2007 [PubMed 17597759]).[supplied by OMIM]

PMID: 9422389