MUL1 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human MUL1. The exact sequence is proprietary.
|
| Localization |
Mitochondrion outer membrane; Multi-pass membrane protein; Peroxisome
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
MUL1
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
40 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Expected cross reactivity based on sequence homology: Rhesus Monkey.
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for MUL1 Antibody
- C1orf166mitochondrial E3 ubiquitin ligase 1
- E3 ubiquitin-protein ligase MUL1
- EC 6.3.2
- EC 6.3.2.-
- FLJ12875
- GIDERP11-401M16.2
- Growth inhibition and death E3 ligase
- MAPLE3 ubiquitin ligase
- mitochondrial E3 ubiquitin protein ligase 1
- mitochondrial ubiquitin ligase activator of NFKB 1
- mitochondrial ubiquitin ligase activator of NF-kB
- Mitochondrial-anchored protein ligase
- MULANchromosome 1 open reading frame 166
- Putative NF-kappa-B-activating protein 266
- RING finger protein 218
- RNF218mitochondria-anchored protein ligase
Background
E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.