IRAK4 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human IRAK4. The exact sequence is proprietary.
|
| Isotype |
IgG
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| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
IRAK4
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
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| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
52 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Expected cross reactivity based on sequence homology: Pig (82%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 20% Glycerol
|
| Preservative |
0.01% Thimerosal
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| Concentration |
0.76 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for IRAK4 Antibody
- EC 2.7.11
- EC 2.7.11.1
- interleukin-1 receptor-associated kinase 4
- IPD1
- IRAK4
- IRAK-4
- NY-REN-64
- REN64
- Renal carcinoma antigen NY-REN-64
Background
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. [supplied by RefSeq]