DECR2 Antibody

Product: Danusertib

DECR2 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human DECR2. The exact sequence is proprietary.
Localization
Peroxisome
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DECR2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunocytochemistry/Immunofluorescence 1:100-1:1000
  • Immunohistochemistry 10 – 1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000
Application Notes
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
31 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 20% Glycerol
Preservative
0.01% Thimerosal
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for DECR2 Antibody

  • 2,4-dienoyl CoA reductase 2, peroxisomal
  • EC 1.3.1
  • EC 1.3.1.34
  • pDCR2,4-dienoyl-CoA reductase 2
  • PDCRshort chain dehydrogenase/reductase family 17C, member 1
  • peroxisomal 2,4-dienoyl-CoA reductase
  • SDR17C1

Background

Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid.

PMID: 19845674