ARFGAP3 Antibody Summary
| Immunogen |
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ARFGAP3. The exact sequence is proprietary.
|
| Localization |
Cytoplasm, Golgi apparatus membrane
|
| Predicted Species |
Mouse (92%), Rat (92%), Primate (100%), Bovine (92%), Chicken (92%). Backed by our 100% Guarantee.
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
ARFGAP3
|
| Purity |
Immunogen affinity purified
|
| Innovators Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
|
Applications/Dilutions
| Dilutions |
|
Reactivity Notes
Expected cross reactivity based on sequence homology: Xenopus laevis (85%), Xenopus Tropicalis (85%), Rhesus Monkey (100%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
0.42 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for ARFGAP3 Antibody
- ADP-ribosylation factor GTPase activating protein 1
- ADP-ribosylation factor GTPase activating protein 3
- ADP-ribosylation factor GTPase-activating protein 3
- ARF GAP 3
- ARFGAP1
- FLJ45618
Background
The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene. [provided by RefSeq]