Product: Rotigotine (Hydrochloride)
WHSC1 Antibody Summary
| Immunogen |
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human NSD2. The exact sequence is proprietary.
|
| Localization |
Nucleus, Isoform 4: Cytoplasm
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
WHSC1
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Theoretical MW |
152 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Expected cross reactivity based on sequence homology: Mouse (83%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for WHSC1 Antibody
- EC 2.1.1.43
- FLJ23286
- IL5 promoter REII region-binding protein
- KIAA1090
- MGC176638
- MMSETNSD2Multiple myeloma SET domain-containing protein
- multiple myeloma SET domain containing protein type III
- Nuclear SET domain-containing protein 2
- probable histone-lysine N-methyltransferase NSD2
- Protein trithorax-5
- REIIBP
- trithorax/ash1-related protein 5
- TRX5
- WHS
- Wolf-Hirschhorn syndrome candidate 1 protein
- Wolf-Hirschhorn syndrome candidate 1
Background
This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences. [provided by RefSeq]