ERK2 Antibody Summary
| Immunogen |
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human ERK2. The exact sequence is proprietary.
|
| Predicted Species |
Porcine (100%), Bovine (100%), Canine (100%). Backed by our 100% Guarantee.
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
MAPK1
|
| Purity |
Immunogen affinity purified
|
| Innovators Reward |
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|
Applications/Dilutions
| Dilutions |
|
| Theoretical MW |
41 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.0) and 40% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for ERK2 Antibody
- EC 2.7.11
- EC 2.7.11.24
- ERK
- ERK2
- ERK-2
- ERK2MAP kinase isoform p42
- ERT1
- Extracellular signal-regulated kinase 2
- MAP kinase 1
- MAP kinase 2
- MAPK 1
- MAPK1
- MAPK2
- mitogen-activated protein kinase 1
- Mitogen-activated protein kinase 2
- p38
- p40
- p41
- p41mapk
- p42mapk
- p42-MAPK
- PRKM1
- PRKM1MAPK 2
- PRKM2
- protein tyrosine kinase ERK2
Background
ERK2 (also designated extracellular-signal-related kinase 2 or mitogen-activated protein kinase 1), with 360-amino acid protein (about 40kDa), belongs to the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of ERK2 requires its phosphorylation by upstream kinases. ERK2 is located in the cytoplasm of resting cells and translocates into the nucleus upon extracellular stimuli by active transport of a dimer. ERK2 is essential for placental development and ERK2 in the trophoblast compartment may be indispensable for the vascularization of the labyrinth.