proBDNF Antibody Summary
| Immunogen |
A synthetic peptide as a part of rat, mouse, zebra fish proBDNF conjugated to an immunogenic carrier protein was used as the immunogen.
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| Specificity |
proBDNF.
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| Clonality |
Polyclonal
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| Host |
Sheep
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| Gene |
BDNF
|
| Purity |
IgG purified
|
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Applications/Dilutions
| Dilutions |
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Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS
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| Preservative |
No Preservative
|
| Concentration |
LYOPH
|
| Purity |
IgG purified
|
| Reconstitution Instructions |
Reconstitute with 0.5 ml sterilized water. Add glycerol (1:1) for additional stability.
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Alternate Names for proBDNF Antibody
- abrineurin
- brain-derived neurotrophic factor
- MGC34632
- neurotrophin
Background
FUNCTION: Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. SUBUNIT: Monomers and homodimers. Binds to NTRK2/TRKB. SUBCELLULAR LOCATION: Secreted.