ALDH6A1 Antibody Summary
| Immunogen |
Peptide with sequence C-SRSSFRGDTN corresponding to internal region according to NP_005580.1.
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| Epitope |
C-SRSSFRGDTN
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| Clonality |
Polyclonal
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| Host |
Goat
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| Gene |
ALDH6A1
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
WB: Approx. 55 kDa band observed in human, mouse and rat kidney lysates (calculated MW of 57.8 kDa band according to NP_005580.1). IHC-P: Human liver shows textured staining of the cytoplasm consistent with mitochondria.
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| Publications |
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Reactivity Notes
Predicted cross-reactivity based on sequence identity: Canine, Bovine, Porcine.
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
|
| Buffer |
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
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| Preservative |
0.02% Sodium Azide
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| Concentration |
0.5 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for ALDH6A1 Antibody
- aldehyde dehydrogenase 6 family, member A1
- Aldehyde dehydrogenase family 6 member A1
- EC 1.2.1.18
- EC 1.2.1.27
- Malonate-semialdehyde dehydrogenase [acylating]
- malonate-semialdehyde dehydrogenase
- methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial
- MGC40271
- MMSADHA
- MMSDHmitochondrial acylating methylmalonate-semialdehyde dehydrogenase
Background
This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.