ADAM33 Antibody

Product: DMP 777

ADAM33 Antibody Summary

Immunogen
Peptide with sequence CQSRRCRKNAFQEL corresponding to internal region according to NP_079496.1.
Specificity
This antibody is expected to recognise isoform alpha (NP_079496.1) and not isoform beta (NP_694882.1).
Clonality
Polyclonal
Host
Goat
Gene
ADAM33
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 0.1 – 0.3 ug/ml
  • Peptide ELISA Detection limit 1:64000
Application Notes
WB: Experiments gave bands at approx. 80-90 kDa band and strong ladder from 26 to 38 kDa band in human prostate lysates after 0.3ug/ml antibody staining. The observation of multiple bands and the 38 kDa band correspond to earlier findings in scientific literature with different antibodies (PMID: 14742294). This protein has a calculated MW of 87.7 kDa band according to NP_079496.1.
Positive Control
Prostate Lysate (NB820-59249)
ADAM33 Lysate (NBL1-07313)
Publications
Read Publications using NB100-1787.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for ADAM33 Antibody

  • a disintegrin and metalloprotease 33
  • a disintegrin and metalloproteinase domain 33
  • ADAM 33
  • ADAM metallopeptidase domain 33
  • ADAM33
  • C20orf153
  • chromosome 20 open reading frame 153
  • disintegrin and metalloproteinase domain-containing protein 33
  • disintegrin and reprolysin metalloproteinase family protein
  • dJ964F7.1
  • DKFZp434K0521
  • EC 3.4.24.-
  • FLJ35308
  • FLJ36751
  • MGC149823
  • MGC71889

Background

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

PMID: 2465070