Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody Summary
| Immunogen |
Peptide with sequence C-DKRRWRKIPKRPGSVH corresponding to C-Terminus according to NP_000729.2.
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| Clonality |
Polyclonal
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| Host |
Goat
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| Gene |
CHRM1
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
WB: Approx. 50 kDa band observed in mouse heart and rat heart lysates (calculated MW of 51.4 kDa band according to NP_000729.2).
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| Positive Control |
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| Publications |
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Reactivity Notes
Predicted cross-reactivity based on sequence identity: Mouse, Rat, Canine.
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
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| Buffer |
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
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| Preservative |
0.02% Sodium Azide
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| Concentration |
0.5 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody
- cholinergic receptor, muscarinic 1
- CHRM1
- HM1
- M1
- M1R
- mAChR M1
- MGC30125
- muscarinic acetylcholine receptor M1
Background
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.