LHR Antibody Summary
| Immunogen |
Peptide with sequence CQGTALLDKTRYTE corresponding to C-Terminus according to NP_000224.2.
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| Clonality |
Polyclonal
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| Host |
Goat
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| Gene |
LHCGR
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| Purity |
Immunogen affinity purified
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| Innovators Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions
| Dilutions |
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| Application Notes |
WB: Preliminary experiments gave an approx. 35 kDa band in lysates of human brain, placenta and prostate and of cell lines Daudi, HeLa and K562 after 0.1 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 78.6 kDa band according to NP_000224.2. The 35 kDa band was successfully blocked by incubation with the immunizing peptide.
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| Publications |
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Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
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| Buffer |
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
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| Preservative |
0.02% Sodium Azide
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| Concentration |
0.5 mg/ml
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| Purity |
Immunogen affinity purified
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Notes
Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at [email protected] for more details.
Alternate Names for LHR Antibody
- CGR
- FLJ41504
- HHG
- hypergonadotropic hypogonadism
- LCGR
- LCGRLH/CGR
- LGR2
- LH/CG-R
- LHCGR
- LHR
- LHRHR
- LHRLGR2ULG5
- LSH-R
- Luteinizing hormone receptor
- luteinizing hormone/choriogonadotropin receptor
- lutropin/choriogonadotropin receptor
- lutropin-choriogonadotropic hormone receptor
- ULG5
Background
LHCGR encodes the receptor for both luteinizing hormone and choriogonadotropin. Mutations in this gonadotropin receptor result in disorders of male secondary sexual character development, such as familial male precocious puberty and male pseudohermaphtoditism.