Product: CCT241533 (hydrochloride)
ECM-1/Secretory Component P85 Antibody (SPM217) – IHC-Prediluted Summary
| Immunogen |
Secretory Component protein isolated from human colostrum
|
| Localization |
Cell surface and cytoplasmic
|
| Specificity |
This MAb reacts with a reduction-resistant epitope present in both free and SIgA bound Secretory Component. It does not react with the cell lines lacking secretory component. The antibody is useful for studying the distribution and level of both free and bound secretory component. Secretory component is differentially expressed in epithelium, and the antibody is a popular marker for identifying subpopulations of epithelial cells and epithelial differentiation. The Secretory component antibody is a useful research tool for studying mucosal immunity, inflammation, remodeling, differentiation and tumorigenesis, all processes associated with differential secretory component expression.
|
| Isotype |
IgG1 Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
ECM1
|
| Purity |
Protein A or G purified
|
| Innovators Reward |
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Applications/Dilutions
| Dilutions |
|
| Application Notes |
Hu-chromosome location: 1q21.2
Molecular weight of antigen: ~80kDa Immunohistochemistry-Paraffin 0.5 – 1 ug/ml for 30 minutes at RT; Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10 – 20 min followed by cooling at RT for 20 minutes. |
Packaging, Storage & Formulations
| Storage |
Store at 4C.
|
| Buffer |
10mM PBS and 0.05% BSA
|
| Preservative |
0.05% Sodium Azide
|
| Purity |
Protein A or G purified
|
Alternate Names for ECM-1/Secretory Component P85 Antibody (SPM217) – IHC-Prediluted
- ECM1
- ECM-1
- extracellular matrix protein 1
- p85
- Secretory Component Glycoprotein
- Secretory Component P85