NGF R/TNFRSF16/p75NTR Antibody (NGFR5 + NTR/912) – Azide and BSA Free

Product: Olprinone (Hydrochloride)

NGF R/TNFRSF16/p75NTR Antibody (NGFR5 NTR/912) – Azide and BSA Free Summary

Immunogen
NGFR from A875 melanoma cells (NGFR5); Recombinant human p75 NGFR protein (NTR/912)
Localization
Cell surface and cytoplasmic
Marker
Soft Tissue Tumor Marker
Specificity
It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts.
Isotype
IgG
Clonality
Monoclonal
Host
Mouse
Gene
NGFR
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry : 0.5 – 1 ug/million cells in 0.1 ml
  • Immunohistochemistry-Paraffin : 0.5 – 1.0 ug/ml
  • CyTOF-ready
  • Immunofluorescence : 1 – 2 ug/ml
Application Notes
Hu-chromosome location: 17q21-22 Immunohistochemistry-Paraffin 0.5 – 1 ug/ml for 30 minutes at RT; Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10 – 20 min followed by cooling at RT for 20 minutes. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
75 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
No Preservative
Concentration
1.0 mg/ml
Purity
Protein A or G purified

Alternate Names for NGF R/TNFRSF16/p75NTR Antibody (NGFR5 NTR/912) – Azide and BSA Free

  • CD271 antigen
  • CD271
  • Gp80-LNGFR
  • member 16
  • nerve growth factor receptor
  • NGF R
  • NGF receptor
  • NGFR
  • p75 ICD
  • p75 NTR
  • TNFRSF16
  • TNFRSF16nerve growth factor receptor (TNFR superfamily, member 16)
  • tumor necrosis factor receptor superfamily member 16

PMID: 15930314