CD3 epsilon Antibody (APA1/1) [PE] Summary
Immunogen |
Purified human CD3 proteins isolated from thymus
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Specificity |
The mouse monoclonal antibody APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation. APA1/1 provides the earliest known marker for TCR-mediated T cell activation.
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Isotype |
IgG1
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Clonality |
Monoclonal
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Host |
Mouse
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Gene |
CD3E
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Purity |
Protein A purified
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Applications/Dilutions
Dilutions |
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Application Notes |
This antibody is useful in Flow Cytometry, Immunoprecipitation, Western Blotting, Immunohistochemistry-frozen and Immunocytochemistry
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Reactivity Notes
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark.
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Buffer |
PBS
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Preservative |
0.05% Sodium Azide
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Purity |
Protein A purified
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Alternate Names for CD3 epsilon Antibody (APA1/1) [PE]
- CD3 epsilon
- CD3e antigen
- CD3e antigen, epsilon polypeptide (TiT3 complex)
- CD3e molecule, epsilon (CD3-TCR complex)
- CD3e
- CD3-epsilon
- FLJ18683
- T3E
- T-cell antigen receptor complex, epsilon subunit of T3
- T-cell surface antigen T3/Leu-4 epsilon chain
- T-cell surface glycoprotein CD3 epsilon chain
- TCRE