P2Y6/P2RY6 Antibody Summary
| Immunogen |
Synthetic 17 amino acid peptide from 2nd cytoplasmic domain of human P2RY6 / P2Y6.
|
| Localization |
Integral plasma membane protein.
|
| Specificity |
Human P2RY6 / P2Y6. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except MOGAT1 (47%).
|
| Predicted Species |
Mouse (94%), Bat (94%), Canine (94%). Backed by our 100% Guarantee.
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
P2RY6
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
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Reactivity Notes
Gorilla, Orangutan, Gibbon, Marmoset. Predicted cross-reactivity based on sequence identity: Panda (94%), Elephant (82%), Pufferfish (82%).
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS
|
| Preservative |
0.1% Sodium Azide
|
| Concentration |
1.0 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for P2Y6/P2RY6 Antibody
- G-coupled nucleotide receptor
- MGC15335
- P2 purinoceptor
- P2RY6
- P2Y6 receptor
- P2Y6
- P2Y6P2Y purinoceptor 6
- pyrimidinergic receptor P2Y, G-protein coupled, 6
Background
The purinergic receptor P2Y6 (P2RY6) is a member of the Purinergic Receptor subfamily. P2 receptors mediate a wide variety of physiologic effects in response to extracellular nucleotides. P2Y6 is believed to play a role in placental function and innate immune defense. P2Y6 expression has been documented in various blood cells, bone marrow, brain, colon, heart, kidney, ovary, placenta, spleen,and thymus. ESTs have been isolated from cervix, embryo, eye, kidney, liver/spleen, placenta, and vessel libraries.