Product: Sulfacetamide (sodium monohydrate)
SOS1 Antibody Summary
| Immunogen |
Synthetic peptide QPTSKAYSPRYSISD from internal region of human SOS1 (NP_005624.2).
|
| Specificity |
Human SOS1.
|
| Predicted Species |
Equine (93%). Backed by our 100% Guarantee.
|
| Clonality |
Polyclonal
|
| Host |
Goat
|
| Gene |
SOS1
|
| Purity |
Immunogen affinity purified
|
| Innovators Reward |
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|
Applications/Dilutions
| Dilutions |
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Reactivity Notes
Gorilla, Gibbon, Marmoset. Predicted cross-reactivity based on sequence identity: Panda (100%), Elephant (87%), Turkey (80%), Chicken (80%), Platypus (80%), Lizard (80%).
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
|
| Buffer |
TBS (pH 7.3) and 0.5% BSA
|
| Preservative |
0.02% Sodium Azide
|
| Concentration |
0.5 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for SOS1 Antibody
- GF1GGF1
- GINGF
- guanine nucleotide exchange factor
- HGFhereditary, 1
- NS4
- son of sevenless homolog 1 (Drosophila)
- son of sevenless homolog 1
- SOS-1
Background
This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4.