Rabbit anti-FCRL4 Polyclonal Antibody

Product Name :
Rabbit anti-FCRL4 Polyclonal Antibody

Synonym :
CD307d; FCRH4; IGFP2; IRTA1

Host :
Rabbit

Species Reactivity:
Human, Mouse, Rat

Specificity :

Predicted Reactivity:

Applications :
WB 1:500 – 1:2000IHC 1:100 – 1:200

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 120-387 of human FCRL4 (NP_112572.1).

Concentration :

Purification :
Affinity purification

Clonality:

Storage Temp.:
Store at -20 ℃Avoid freeze / that cycles

Research areas :

Background :
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma.

UniProt :
Q96PJ5

Additional information:
Product Details FAQ Citations(0) Video Pictures Documents |Overview |Synonym CD307d; FCRH4; IGFP2; IRTA1 |Host Rabbit |Species Reactivity Human, Mouse, Rat |Applications WB 1:500 – 1:2000IHC 1:100 – 1:200 |Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 120-387 of human FCRL4 (NP_112572.1). |Positive control Raji,B-cell,293T,Mouse kidney,Mouse liver,Rat kidney,Rat liver |Properties |Purification Affinity purification |Isotype IgG |Storage Temp. Store at -20 ℃Avoid freeze / that cycles |Storage Buffer Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |Target |Background This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma. |Cellular localization Cell membrane,Single-pass type I membrane protein |UniProt Q96PJ5 |Tips:This product is for research use only. Not for use in diagnostic prodcedures.

Rabbit anti-FCRL4 Polyclonal Antibody

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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