Product Name :
4-Hydroxytolbutamide
Description:
4-Hydroxytolbutamide (Hydroxytolbutamide) is a metabolite of Tolbutamide. 4-Hydroxytolbutamide is metabolized by CYP2C8 and CYP2C9. Tolbutamide is a first generation potassium channel blocker and a sulfonylurea oral antidiabetic.
CAS:
5719-85-7
Molecular Weight:
286.35
Formula:
C12H18N2O4S
Chemical Name:
3-butyl-1-[4-(hydroxymethyl)benzenesulfonyl]urea
Smiles :
CCCCNC(=O)NS(=O)(=O)C1=CC=C(CO)C=C1
InChiKey:
SJRHYONYKZIRPM-UHFFFAOYSA-N
InChi :
InChI=1S/C12H18N2O4S/c1-2-3-8-13-12(16)14-19(17,18)11-6-4-10(9-15)5-7-11/h4-7,15H,2-3,8-9H2,1H3,(H2,13,14,16)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
4-Hydroxytolbutamide (Hydroxytolbutamide) is a metabolite of Tolbutamide. 4-Hydroxytolbutamide is metabolized by CYP2C8 and CYP2C9. Tolbutamide is a first generation potassium channel blocker and a sulfonylurea oral antidiabetic.|Product information|CAS Number: 5719-85-7|Molecular Weight: 286.35|Formula: C12H18N2O4S|Synonym:|Hydroxytolbutamide|Chemical Name: 3-butyl-1-[4-(hydroxymethyl)benzenesulfonyl]urea|Smiles: CCCCNC(=O)NS(=O)(=O)C1=CC=C(CO)C=C1|InChiKey: SJRHYONYKZIRPM-UHFFFAOYSA-N|InChi: InChI=1S/C12H18N2O4S/c1-2-3-8-13-12(16)14-19(17,18)11-6-4-10(9-15)5-7-11/h4-7,15H,2-3,8-9H2,1H3,(H2,13,14,16)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Ipilimumab CTLA-4 |Shelf Life: ≥12 months if stored properly.QX-314 TGF-beta/Smad |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:33121378 |Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Hansen LL, et al. Quantitative determination of tolbutamide and its metabolites in human plasma and urine by high-performance liquid chromatography and UV detection. Ther Drug Monit. 1999 Dec;21(6):664-71.Yuan R, et al. Evaluation of cytochrome P450 probe substrates commonly used by the pharmaceutical industry to study in vitro drug interactions. Drug Metab Dispos. 2002 Dec;30(12):1311-9.Products are for research use only. Not for human use.|