Product Name :
LDN-193189 2HCl
CAS No.:
1435934-00-1
Purity :
> 97%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
Cl.C1CN(CCN1)C2=CC=C(C=C2)C3=C[N]4N=CC(=C4N=C3)C5=CC=NC6=C5C=CC=C6
Product Description :
LDN193189 HCl is the hydrochloride salt of LDN193189, which is a selective BMP signaling inhibitor, and inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM in C2C12 cell lines, respectively, 200-fold selectivity for BMP versus TGF-β.
Formula:
C25H23ClN6
Molecular Weight :
479.4
Synonyms:
Additional Information:
|CAS No. 1435934-00-1 ; |Formula C25H23ClN6 ; |Molecular Weight 479.4 ; |SMILES Cl.C1CN(CCN1)C2=CC=C(C=C2)C3=C[N]4N=CC(=C4N=C3)C5=CC=NC6=C5C=CC=C6 ; |Product Description LDN193189 HCl is the hydrochloride salt of LDN193189, which is a selective BMP signaling inhibitor, and inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM in C2C12 cell lines, respectively, 200-fold selectivity for BMP versus TGF-β.{{2326521-71-3} MedChemExpress|{2326521-71-3} Purity & Documentation|{2326521-71-3} In Vivo|{2326521-71-3} custom synthesis} ; |Purity > 97% ; |Shipping Shipped on dry ice.{{1640294-30-9} MedChemExpress|{1640294-30-9} Purity & Documentation|{1640294-30-9} Purity|{1640294-30-9} supplier} ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in water and in DMSO