Product Name :
AG-014699(PF-01367338)
Description:
Rucaparib (AG014699) is an orally active and potent inhibitor of PARP with Ki of 1.4 nM for PARP1 in a cell-free assay. Rucaparib shows binding affinity to eight other PARP domains.
CAS:
283173-50-2
Molecular Weight:
323.36
Formula:
C19H18FN3O
Chemical Name:
6-fluoro-2-{4-[(methylamino)methyl]phenyl}-3, 10-diazatricyclo[6.4.1.0, ]trideca-1, 4, 6, 8(13)-tetraen-9-one
Smiles :
CNCC1C=CC(=CC=1)C1NC2=CC(F)=CC3C(=O)NCCC=1C=32
InChiKey:
HMABYWSNWIZPAG-UHFFFAOYSA-N
InChi :
InChI=1S/C19H18FN3O/c1-21-10-11-2-4-12(5-3-11)18-14-6-7-22-19(24)15-8-13(20)9-16(23-18)17(14)15/h2-5,8-9,21,23H,6-7,10H2,1H3,(H,22,24)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Rucaparib (AG014699) is an orally active and potent inhibitor of PARP with Ki of 1.{{Farnesol} web|{Farnesol} Anti-infection|{Farnesol} NF-κB|{Farnesol} Biological Activity|{Farnesol} Purity|{Farnesol} manufacturer} 4 nM for PARP1 in a cell-free assay. Rucaparib shows binding affinity to eight other PARP domains.|Product information|CAS Number: 283173-50-2|Molecular Weight: 323.36|Formula: C19H18FN3O|Synonym:|AG-14699|AG014447 (as free base)|PF-01367338|Rucaparib free base|Rubraca|Related CAS Number:|459868-92-9 (Rucaparib phosphate)|1859053-21-6 (Rucaparib Camsylate)|Chemical Name: 6-fluoro-2-{4-[(methylamino)methyl]phenyl}-3, 10-diazatricyclo[6.{{Tauro-β-muricholic acid} MedChemExpress|{Tauro-β-muricholic acid} Metabolic Enzyme/Protease|{Tauro-β-muricholic acid} NF-κB|{Tauro-β-muricholic acid} Purity & Documentation|{Tauro-β-muricholic acid} In stock|{Tauro-β-muricholic acid} custom synthesis} 4.1.0, ]trideca-1, 4, 6, 8(13)-tetraen-9-one|Smiles: CNCC1C=CC(=CC=1)C1NC2=CC(F)=CC3C(=O)NCCC=1C=32|InChiKey: HMABYWSNWIZPAG-UHFFFAOYSA-N|InChi: InChI=1S/C19H18FN3O/c1-21-10-11-2-4-12(5-3-11)18-14-6-7-22-19(24)15-8-13(20)9-16(23-18)17(14)15/h2-5,8-9,21,23H,6-7,10H2,1H3,(H,22,24)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:25269910 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|