Product Name :
Mal-PEG1-PFP ester
Description:
Mal-PEG1-PFP ester is a Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.
CAS:
1807530-08-0
Molecular Weight:
379.24
Formula:
C15H10F5NO5
Chemical Name:
2,3,4,5,6-pentafluorophenyl 3-[2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]propanoate
Smiles :
O=C(CCOCCN1C(=O)C=CC1=O)OC1C(F)=C(F)C(F)=C(F)C=1F
InChiKey:
ZKWVOGYIIBUFNC-UHFFFAOYSA-N
InChi :
InChI=1S/C15H10F5NO5/c16-10-11(17)13(19)15(14(20)12(10)18)26-9(24)3-5-25-6-4-21-7(22)1-2-8(21)23/h1-2H,3-6H2
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Etrolizumab} site|{Etrolizumab} Cytoskeleton|{Etrolizumab} Biological Activity|{Etrolizumab} Purity|{Etrolizumab} supplier|{Etrolizumab} Epigenetic Reader Domain}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Nervonic acid} MedChemExpress|{Nervonic acid} Endogenous Metabolite|{Nervonic acid} Technical Information|{Nervonic acid} In Vivo|{Nervonic acid} custom synthesis|{Nervonic acid} Epigenetics}
Additional information:
Mal-PEG1-PFP ester is a Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.PMID:36717102 |Product information|CAS Number: 1807530-08-0|Molecular Weight: 379.24|Formula: C15H10F5NO5|Chemical Name: 2,3,4,5,6-pentafluorophenyl 3-[2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]propanoate|Smiles: O=C(CCOCCN1C(=O)C=CC1=O)OC1C(F)=C(F)C(F)=C(F)C=1F|InChiKey: ZKWVOGYIIBUFNC-UHFFFAOYSA-N|InChi: InChI=1S/C15H10F5NO5/c16-10-11(17)13(19)15(14(20)12(10)18)26-9(24)3-5-25-6-4-21-7(22)1-2-8(21)23/h1-2H,3-6H2|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|