Product Name :
Vps34-IN-1
Description:
Vps34-IN-1 is an inhibitor of Vps34 extracted from patent WO2012085815A1, compound example 16a, with an IC50 of 4 nM. Vps34-IN-1 modulates autophagy.
CAS:
1383716-33-3
Molecular Weight:
425.91
Formula:
C21H24ClN7O
Chemical Name:
1-({2-[(2-chloropyridin-4-yl)amino]-4′-(cyclopropylmethyl)-[4,5′-bipyrimidin]-2′-yl}amino)-2-methylpropan-2-ol
Smiles :
CC(C)(O)CNC1N=C(CC2CC2)C(=CN=1)C1=CC=NC(NC2C=C(Cl)N=CC=2)=N1
InChiKey:
AWNXKZVIZARMME-UHFFFAOYSA-N
InChi :
InChI=1S/C21H24ClN7O/c1-21(2,30)12-26-19-25-11-15(17(29-19)9-13-3-4-13)16-6-8-24-20(28-16)27-14-5-7-23-18(22)10-14/h5-8,10-11,13,30H,3-4,9,12H2,1-2H3,(H,25,26,29)(H,23,24,27,28)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Lansoprazole} web|{Lansoprazole} Membrane Transporter/Ion Channel|{Lansoprazole} Biological Activity|{Lansoprazole} In Vivo|{Lansoprazole} manufacturer|{Lansoprazole} Epigenetic Reader Domain}
Shelf Life:
≥12 months if stored properly.{{Gemtuzumab} MedChemExpress|{Gemtuzumab} Antibody-drug Conjugate/ADC Related|{Gemtuzumab} Protocol|{Gemtuzumab} In Vitro|{Gemtuzumab} manufacturer|{Gemtuzumab} Epigenetic Reader Domain}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Vps34-IN-1 is an inhibitor of Vps34 extracted from patent WO2012085815A1, compound example 16a, with an IC50 of 4 nM. Vps34-IN-1 modulates autophagy.|Product information|CAS Number: 1383716-33-3|Molecular Weight: 425.91|Formula: C21H24ClN7O|Chemical Name: 1-({2-[(2-chloropyridin-4-yl)amino]-4′-(cyclopropylmethyl)-[4,5′-bipyrimidin]-2′-yl}amino)-2-methylpropan-2-ol|Smiles: CC(C)(O)CNC1N=C(CC2CC2)C(=CN=1)C1=CC=NC(NC2C=C(Cl)N=CC=2)=N1|InChiKey: AWNXKZVIZARMME-UHFFFAOYSA-N|InChi: InChI=1S/C21H24ClN7O/c1-21(2,30)12-26-19-25-11-15(17(29-19)9-13-3-4-13)16-6-8-24-20(28-16)27-14-5-7-23-18(22)10-14/h5-8,10-11,13,30H,3-4,9,12H2,1-2H3,(H,25,26,29)(H,23,24,27,28)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : ≥ 31 mg/mL (72.PMID:24187611 79 mM).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|