Product Name :
Propargyl-PEG6-NHS ester
Description:
Propargyl-PEG6-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG6-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
CAS:
2093153-99-0
Molecular Weight:
445.46
Formula:
C20H31NO10
Chemical Name:
2,5-dioxopyrrolidin-1-yl 4,7,10,13,16,19-hexaoxadocos-21-ynoate
Smiles :
C#CCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O
InChiKey:
WVFFBCAEFRYUEY-UHFFFAOYSA-N
InChi :
InChI=1S/C20H31NO10/c1-2-6-25-8-10-27-12-14-29-16-17-30-15-13-28-11-9-26-7-5-20(24)31-21-18(22)3-4-19(21)23/h1H,3-17H2
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Propargyl-PEG6-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG6-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).{{Amlodipine besylate} medchemexpress|{Amlodipine besylate} Membrane Transporter/Ion Channel|{Amlodipine besylate} Protocol|{Amlodipine besylate} Purity|{Amlodipine besylate} supplier|{Amlodipine besylate} Autophagy} |Product information|CAS Number: 2093153-99-0|Molecular Weight: 445.{{Lorlatinib} site|{Lorlatinib} ROS Kinase|{Lorlatinib} Purity & Documentation|{Lorlatinib} In stock|{Lorlatinib} manufacturer|{Lorlatinib} Epigenetics} 46|Formula: C20H31NO10|Chemical Name: 2,5-dioxopyrrolidin-1-yl 4,7,10,13,16,19-hexaoxadocos-21-ynoate|Smiles: C#CCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O|InChiKey: WVFFBCAEFRYUEY-UHFFFAOYSA-N|InChi: InChI=1S/C20H31NO10/c1-2-6-25-8-10-27-12-14-29-16-17-30-15-13-28-11-9-26-7-5-20(24)31-21-18(22)3-4-19(21)23/h1H,3-17H2|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:24580853 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.|Products are for research use only. Not for human use.|