Product: YHO-13351 (free base)
Frizzled-8 Antibody Summary
| Immunogen |
Synthetic 16 amino acid peptide from 3rd extracellular domain of human FZD8 / Frizzled 8.
|
| Localization |
Cell Membrane; multi-pass membrane protein
|
| Specificity |
Human FZD8 / Frizzled 8. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except INTS6 (50%).
|
| Predicted Species |
Opossum (100%). Backed by our 100% Guarantee.
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
FZD8
|
| Purity |
Immunogen affinity purified
|
| Innovators Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
|
Applications/Dilutions
| Dilutions |
|
Reactivity Notes
Predicted cross-reactivity based on sequence identity: Marmoset (100%), Elephant (100%), Panda (100%), Lizard (94%), Monkey (81%).
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS
|
| Preservative |
0.1% Sodium Azide
|
| Concentration |
1.0 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for Frizzled-8 Antibody
- frizzled (Drosophila) homolog 8
- frizzled 8
- frizzled family receptor 8
- frizzled homolog 8 (Drosophila)
- Frizzled8
- Frizzled-8
- FZ-8
- FZD8
- hFZ8
Background
Frizzled-8 Antibody is a Frizzled Receptor that mediates Wnt signaling and is involved in determining vertebrate axis and tissue polarity. Frizzled-8 Antibody is expressed during embryonic development in forming and differentiating somites in mice. Frizzled-8 Antibody expression has been reported in brain, heart, kidney, pancreas, and skeletal muscle. ESTs have been isolated from embryo, eye, head/neck, heart, kidney, liver/spleen, pancreas, prostate, and testis libraries, as well as many tumor libraries.