Hritis Rheum. 40, 1612?04 (1997). two. Cho, J. H. Feldman, M. Heterogeneity of autoimmune ailments: pathophysiologic insights from genetics and implications for new therapies. Nat. Med. 21, 730?38 (2015). 3. Ruffatti, A. et al. Anti-double-stranded DNA antibodies within the healthier elderly: prevalence and characteristics. J. Clin. Immunol. 10, 300?03 (1990). four. Rubin, R. L., Teodorescu, M., Beutner, E. H. Plunkett, R. W. Complement-fixing properties of antinuclear antibodies distinguish drug-induced lupus from systemic lupus Respiratory Inhibitors Reagents erythematosus. Lupus 13, 249?56 (2004). five. DeGiorgio, L. A., Konstantinov, K. N. Diamond, B. A subset of lupus anti-DNA antibodies cross-reacts using the NR2 glutamate receptor in systemic lupus erythematosus. Nat. Med. 7, 1189?193 (2001). six. Sun, K.-H., Yu, C.-L., Tang, S.-J. Sun, G.-H. Monoclonal anti-double-stranded DNA autoantibody stimulates the expression and release of IL-1, IL-6, IL-8, IL-10 and TNF- from regular human mononuclear cells involving in the lupus pathogenesis. Immunology 99, 352?60 (2000). 7. Sprangers, B., Monahan, M. Appel, G. B. Diagnosis and therapy of lupus nephritis flares – an update. Nat. Rev. Nephrology eight, 709?17 (2012). eight. Lau, C. S. Mak, A. The socioeconomic burden of SLE. Nat. Rev. Rheumatol. five, 400?04 (2009). 9. Pisetsky, D. S. Anti-DNA antibodies – quintessential biomarkers of SLE. Nat. Rev. Rheumatol. 12, 102?10 (2016). 10. Liu, C. C., Kao, A. H., Manzi, S. Ahearn, J. M. Biomarkers in systemic lupus erythematosus: challenges and prospects for the future. Ther. Adv. Musculoskelet. Dis. 5, 210?33 (2013). 11. Welsh, R. Vyska, K. Phosphopeptides in extremely purified calf thymusDNA. Standard Appl. Histochem. 31, 281?98 (1987). 12. Porsch, B., Laga, R., Horsk? J., Ko , C. Ulbrich, K. Molecular weight and polydispersity of calf-thymus DNA: static light-scattering and size-exclusion chromatography with dual detection. Biomacromolecules 10, 3148?150 (2009). 13. Sanguineti, S. et al. Certain recognition of a DNA immunogen by its elicited antibody. J. Mol. Biol. 370, 183?95 (2007). 14. Stevens, S. Y., Swanson, P. C., Voss, E. W. Jr. Glick, G. D. Evidence for induced match in antibody-DNA complexes. J. Am. Chem. Soc. 115, 1585?586 (1993). 15. Barbas, S. M., Ghazal, P., Barbas, C. F. III Burton, D. R. Recognition of DNA by synthetic antibodies. J. Am. Chem. Soc. 116, 2161?162 (1994). 16. Tran, T. N. et al. A universal DNA-based protein detection Adenine Receptors Inhibitors Reagents program. J. Am. Chem. Soc. 135, 14008?4011 (2013). 17. An, Y., Raju, R. K., Lu, T. Wheeler, S. E. Aromatic interactions modulate the 5-base selectivity of the DNA-binding autoantibody ED-10. J. Phys. Chem. B 118, 5653?659 (2014). 18. Chiaro, T. R., Davis, K. W., Wilson, A., Suh-Lailam, B. Tebo, A. E. Evaluation of a higher avidity anti-dsDNA IgG enzyme-linked immunosorbent assay for the diagnosis of systemic lupus erythematosus. Clin. Chim. Acta 412, 1076?080 (2011). 19. Pavlovic, M. et al. Pathogenic and Epiphenomenal Anti-DNA Antibodies in SLE. Autoimmune Dis. 2010, Article ID462841 (2010). 20. Fernando, H., Rodriguez, R. Balasubramanian, S. Selective recognition of a DNA G-quadruplex by an engineered antibody. Biochemistry 47, 9365?371 (2008). 21. Brunner, H. I., Huggins, J. Klein-Gitelman, M. S. Pediatric SLE – towards a extensive management program. Nat. Rev. Rheumatol. 7, 225?33 (2011). 22. Samuelsen, S. V. et al. Synthetic oligonucleotide antigens modified with locked nucleic acids detect disease particular antibodies. Sci. Rep. six, 35827 (2016).
Related Posts
cis-4-(Boc-amino)cyclohexylamine, 97%
Product Name : cis-4-(Boc-amino)cyclohexylamine, 97%Synonym: IUPAC Name : CAS NO.:Molecular Weight : Molecular formula: Smiles: Description: cis-4-(Boc-amino)cyclohexylamine can be used in agrochemical, pharmaceutical and dyestuff field.Ceftriaxone Tetrahydroberberine PMID:25558565 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced […]
Charide (LPS).In the similar situation of Nature, Ricote et al. presented evidence that activated macrophages
Charide (LPS).In the similar situation of Nature, Ricote et al. presented evidence that activated macrophages upregulate PPAR.They further demonstrated that ligand bound PPAR inhibits inflammatory gene expression by way of a procedure termed transrepression by targeting certain transcription components which includes NFB, AP, and STAT.Transrepression is any mechanism by which a nuclear receptor, when bound […]
-frequency assessment. They found flat responses out to 10 kHz at room
-frequency assessment. They found flat responses out to 10 kHz at room temperature. Importantly, the direct effects of temperature on OHC displacement currents and NLC have been evaluated and shown to substantially affect NLC Vh (indicative of transition-rate effects) of both OHC and prestintransfected cells when the bath temperature is altered (30,54,55). Shifts of 20 […]