GNPDA2 Antibody

Product: ARQ-092

GNPDA2 Antibody Summary

Immunogen
Antibody was raised against an 8 amino acid synthetic peptide near the carboxy terminus of human GNPDA2. The immunogen is located within the last 50 amino acids of GNPDA2.
Specificity
GNPDA2 antibody is predicted to not cross-react with GNPDA1.
Clonality
Polyclonal
Host
Rabbit
Gene
GNPDA2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 1:10-1:2000
Control Peptide
GNPDA2 Peptide (NBP1-76997PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for GNPDA2 Antibody

  • EC 3.5.99.6
  • GlcN6P deaminase 2
  • glucosamine-6-phosphate deaminase 24921523I18Rik
  • glucosamine-6-phosphate isomerase 2
  • Glucosamine-6-phosphate isomerase SB52
  • GNP2SB52
  • GNPDA 2
  • putative glucosamine-6-phosphate isomerase

Background

Glucosamine-6-phosphate deaminase (GNPDA) is an allosteric enzyme that catalyzes the reversible conversion of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium. GNPDA2 is the second mammalian glucosamine-6-phosphate deaminase discovered, and is closer in structure and activity to the E. coli enzyme than GNPDA1. GNPDA1 possesses greater affinity for ammonium than either GNPDA2 or the E. coli enzyme suggesting that the forward reaction of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium is catalyzed at a slower rate than GNPDA2. GNPDA2 antibody is predicted to not cross-react with GNPDA1.

PMID: 21402471