TRPC3 Antibody Summary
| Immunogen |
Antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human TRPC3. The immunogen is located within amino acids 120 – 170 of TRPC3.
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| Specificity |
This antibody may cross-react with TRPC6 and TRPC7.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
TRPC3
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Theoretical MW |
100 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
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| Control Peptide |
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Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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| Buffer |
PBS
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| Preservative |
0.02% Sodium Azide
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| Concentration |
1 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for TRPC3 Antibody
- hTrp3
- hTrp-3
- short transient receptor potential channel 3
- transient receptor potential cation channel, subfamily C, member 3
- transient receptor potential channel 3
- Transient receptor protein 3
- TRP3
- TRP-3
- TrpC3
Background
The mammalian transient receptor potential (TRP) superfamily can be divided into three major families including the “canonical TRP” (TRPC) family. The seven members of this family share the activation through PLC-coupled receptors and have been suggested to be components of receptor-regulated cation channels in different cell types. Furthermore, the members of the TRPC3/6/7 subfamily can be activated by diacylglycerol analogs, suggesting a possible mechanism of activation of these channels by PLC-coupled receptors. TRPC3 encodes a Ca2+-permeant channel that is agonist-activated but not store-operated or directly receptor-activated. TRPC3 physically interacts with TRPC6 and TRPC7 and forms functional tetrameric channels.