Cullin 1 Antibody Summary
| Immunogen |
Synthetic peptide (Human).
|
| Localization |
Nuclear
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| Specificity |
This reacts with an 86kDa protein, known as Cullin 1.
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
CUL1
|
| Purity |
IgG purified
|
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Immunoprecipitation, Western Blot, Immunohistochemistry – Paraffin and FrozenIHC: This antibody may be diluted to a titer of 1:25-1:75 in an ABC method. We suggest an incubation period of 30 minutes at room temperature.
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| Positive Control |
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Reactivity Notes
Cross-reacts with Human and Mouse.
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
PBS
|
| Preservative |
Sodium Azide
|
| Purity |
IgG purified
|
Alternate Names for Cullin 1 Antibody
- CUL-1
- cullin 1
- cullin-1
- MGC149834
- MGC149835
Background
Cullin 1 may be involved in the degradation of positive cell cycle regulators (for example G1 cyclins in yeast). Human cullin 1 forms a complex with Skp1 and the F box protein Skp2, which is thought to play a role in the ubiquitination of G1 regulatory proteins, as its homolog does in yeast.