Nicotinic Acetylcholine R alpha 3/CHRNA3 Antibody Summary
| Immunogen |
Synthetic peptide derived from CHRNA3 protein
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
CHRNA3
|
| Purity |
Unpurified
|
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Applications/Dilutions
| Dilutions |
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| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
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|
| Theoretical MW |
57 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
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| Publications |
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Reactivity Notes
Chicken reactivity reported in scientific literature (PMID: 26061781)
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
Antiserum
|
| Preservative |
No Preservative
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| Concentration |
LYOPH
|
| Purity |
Unpurified
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| Reconstitution Instructions |
Reconstitute with 0.2 ml distilled water.
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Alternate Names for Nicotinic Acetylcholine R alpha 3/CHRNA3 Antibody
- cholinergic receptor, nicotinic, alpha 3
- cholinergic receptor, nicotinic, alpha polypeptide 3
- CHRNA3
- LNCR2
- MGC104879
- NACHRA3
- neuronal acetylcholine receptor subunit alpha-3
- neuronal nicotinic acetylcholine receptor, alpha3 subunit
- Nicotinic Acetylcholine R alpha 3
- Nicotinic Acetylcholine Ra3
- PAOD2
Background
The nicotinic acetylcholine receptor (nAChR) is a ligand gated ion channel that mediates neurotransmission at the neuromuscular junction, autonomic ganglia and at some sites in the central nervous system. Distinct nAChR subtypes exist that can be stimulated by the neurotransmitter acetylcholine, the natural product nicotine, or by synthetic compounds. After binding acetylcholine, Nicotinic Acetylcholine Receptor alpha 3 responds by an extensive change in conformation that affects all subunits and leads to opening of an ion conducting channel across the plasma membrane.