AXUD1 Antibody Summary
| Immunogen |
AXUD1 protein
|
| Specificity |
Reacts with the human AXUD1 protein.
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
CSRNP1
|
| Purity |
Immunogen affinity purified
|
| Innovators Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
|
Applications/Dilutions
| Dilutions |
|
||
| Application Notes |
Western blot – Use at 1:500 to 1:1,000 dilution. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry-frozen and paraffin.
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
||
| Theoretical MW |
60 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
||
| Positive Control |
|
||
| Publications |
|
Reactivity Notes
Human. Other species not tested.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS
|
| Preservative |
0.02% Sodium Azide
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for AXUD1 Antibody
- AXIN1 up-regulated 1
- Axin-1 up-regulated gene 1 protein
- AXUD1DKFZp566F164
- CSRNP-1
- cysteine/serine-rich nuclear protein 1
- cysteine-serine-rich nuclear protein 1
- FAM130B
- Protein URAX1
- TAIP3
- TAIP-3TGF-beta-induced apoptosis protein 3
- TGF-beta induced apoptosis protein 3
- URAX1
Background
Axin, an important regulator of beta-catenin, is frequently mutated in human hepatocellular carcinomas (HCCs), and transduction of the wild-type Axin gene (AXIN1) induces apoptosis in HCC cells as well as in colon cancer cells. A novel gene, AXUD1 (AXIN 1 up-regulated), has enhanced expression in response to exogenously expressed AXIN1. It is expressed in all human tissues examined, most abundantly in lung, placenta, skeletal muscle, pancreas and leukocytes. Data suggests that AXUD1 may have a tumor-suprressor function in those organs.