MAP1 Antibody Summary
| Immunogen |
residues 337-351 of the human 39 kDa MAP-1 protein.
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| Specificity |
Reacts with residues 337-351 of the human 39 kDa MAP-1 protein.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
MOAP1
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Western blot. The investigator should determine the optimal dilution for a specific application such as immunohistochemistry.
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| Publications |
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Reactivity Notes
Human.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS
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| Preservative |
0.02% Sodium Azide
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| Concentration |
1 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for MAP1 Antibody
- MAP1
- MAP-1PNMA4Paraneoplastic antigen Ma4
- modulator of apoptosis 1
- paraneoplastic antigen like 4
Background
A novel Bax-associating protein, named MAP-1 (Modulator of Apoptosis), mediates caspase-dependent apoptosis in mammalian cells when overexpressed. MAP-1 homodimerizes and associates with the proapoptotic Bax and the prosurvival Bcl-2 and Bcl-X(L) of the Bcl-2 family in vitro and in vivo in mammalian cells. These data suggest that MAP-1 mediates apoptosis through a mechanism that involves binding to Bax.