Frizzled-5 Antibody Summary
| Immunogen |
Synthetic 16 amino acid peptide from N-terminal extracellular domain of human FZD5 / Frizzled 5.
|
| Specificity |
Human FZD5 / Frizzled 5. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
|
| Predicted Species |
Canine (94%), Rabbit (94%). Backed by our 100% Guarantee.
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
FZD5
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
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Reactivity Notes
Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Elephant (100%), Marmoset (88%), Bovine (88%), Porcine (88%).
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS
|
| Preservative |
0.1% Sodium Azide
|
| Concentration |
1.0 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for Frizzled-5 Antibody
- C2orf31
- chromosome 2 open reading frame 31
- DKFZP434E2135
- frizzled (Drosophila) homolog 5
- frizzled homolog 5 (Drosophila)
- Frizzled5
- Frizzled-5
- Frz-5
- FZ-5
- FZD5
- fzE5
- HFZ5
- MGC129692
- seven-transmembrane receptor frizzled-5
- Wnt receptor
Background
FZD5 is a Frizzled Receptor that mediates Wnt signaling. FZD5 is associated with limb bud and bone marrow stem cell development. FZD5 contributes to the activated state of fibroblast-like synoviocytes from patients with rheumatoid arthritis. Recently, FZD5 has been implicated in melanoma metastasis through the Wnt5a and PKC pathway. FZD5 has been reported to be expressed in fetal kidney, fetal and adult liver, fetal lung, and adult pancreas. ESTs have been isolated from bone, liver/spleen, placenta, and prostate libraries. FZD5 was cloned from a retina cDNA library.