Product: Sinapine (thiocyanate)
PRAK Antibody Summary
| Immunogen |
The immunogen for this product maps to a region between residue 250 and 300 of human mitogen-activated protein kinase-activated protein kinase 5 using the numbering given in entry NP_620777.1 (GeneID 8550).
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
MAPKAPK5
|
| Purity |
Immunogen affinity purified
|
| Innovators Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
|
Applications/Dilutions
| Dilutions |
|
Reactivity Notes
Human
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
Tris-Citrate/Phosphate (pH 7.0 – 8.0)
|
| Preservative |
0.09% Sodium Azide
|
| Concentration |
1.0 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for PRAK Antibody
- EC 2.7.11
- MAP kinase-activated protein kinase 5
- MAPK-activated protein kinase 5
- MAPKAP kinase 5
- MAPKAPK-5
- mitogen-activated protein kinase-activated protein kinase 5
- p38-regulated/activated protein kinase
- PRAKEC 2.7.11.1
Background
The protein encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported.